abstract：:We measured total and free plasma concentrations of ropivacaine following high-volume, high-dose local infiltration analgesia in 28 patients aged 65 years or over undergoing unilateral total knee arthroplasty. Patients received infiltration of ropivacaine 400 mg followed by infusion at 20 mg.h(-1) through an intra-art...

journal_title：Anaesthesia

authors： Brydone AS,Souvatzoglou R,Abbas M,Watson DG,McDonald DA,Gill AM

更新日期：2015-07-01 00:00:00

abstract：:For patients with ischaemic heart disease, remote ischaemic conditioning may offer an innovative, non-invasive and virtually cost-free therapy for protecting the myocardium against the detrimental effects of acute ischaemia-reperfusion injury, preserving cardiac function and improving clinical outcomes. The intriguing...

journal_title：Anaesthesia

authors： Sivaraman V,Pickard JM,Hausenloy DJ

更新日期：2015-06-01 00:00:00

abstract：:The concept of haemostatic resuscitation implies early and high-volume plasma transfusion. We investigated the haemostatic profile of reconstituted whole blood prepared in a 1:1:1 ratio of blood, platelets and plasma. This consisted of packed red blood cells, platelet concentrate and four different plasma variants: fr...

journal_title：Anaesthesia

authors： Ponschab M,Schöchl H,Gabriel C,Süssner S,Cadamuro J,Haschke-Becher E,Gratz J,Zipperle J,Redl H,Schlimp CJ

更新日期：2015-05-01 00:00:00

abstract：:Both the American Society of Anesthesiologists and the UK NAP4 project recommend that an unspecified pre-operative airway assessment be made. However, the choice of assessment is ultimately at the discretion of the individual anaesthesiologist. We retrieved a cohort of 188 064 cases from the Danish Anaesthesia Databas...

journal_title：Anaesthesia

authors： Nørskov AK,Rosenstock CV,Wetterslev J,Astrup G,Afshari A,Lundstrøm LH

更新日期：2015-03-01 00:00:00

abstract：:Measurement of left ventricular stroke volume and cardiac output is very important for managing haemodynamically unstable or critically ill patients. The aims of this study were to compare stroke volume measured by three-dimensional transoesophageal echocardiography with stroke volume measured using a pulmonary artery...

journal_title：Anaesthesia

authors： Suehiro K,Tanaka K,Yamada T,Matsuura T,Funao T,Mori T,Nishikawa K

更新日期：2015-02-01 00:00:00

abstract：:Animal studies have shown that injection pressures > 75 kPa indicate probable intrafascicular needle tip position. This study describes the flow/pressure characteristics of seven common needle systems. A syringe pump delivered flow rates of 5, 6.67, 10, 13.3, 15 and 20 ml.min(-1) through these needle systems, while ke...

journal_title：Anaesthesia

authors： Patil JJ,Ford S,Egeler C,Williams DJ

更新日期：2015-02-01 00:00:00

abstract：:A key figure in the development of anaesthesia in Russia was the surgeon Nikolay Ivanovich Pirogov (1810-1881). He experimented with ether and chloroform and organised the general introduction of anaesthesia in Russia for patients undergoing surgery. He was the first to perform systematic research into anaesthesia-rel...

journal_title：Anaesthesia

authors： Hendriks IF,Bovill JG,Boer F,Houwaart ES,Hogendoorn PC

更新日期：2015-02-01 00:00:00

abstract：:Allogeneic red cell transfusion is a commonly used treatment to improve the oxygen carrying capacity of blood during the peri-operative period. Increasing arterial oxygen content by increasing haemoglobin does not necessarily increase tissue oxygen delivery or uptake. Although the evidence-base for red cell transfusio...

journal_title：Anaesthesia

authors： Shah A,Stanworth SJ,McKechnie S

更新日期：2015-01-01 00:00:00

abstract：:The haemostatic management of major obstetric haemorrhage remains challenging, and current published guidance relies heavily on experience from the non-pregnant population and expert opinion. In recent years, an interest in the implications of relative hypofibrinogenaemia, point-of-care monitoring of coagulation abnor...

journal_title：Anaesthesia

authors： Collis RE,Collins PW

更新日期：2015-01-01 00:00:00

abstract：:Effective pain therapy after shoulder surgery is the main prerequisite for safe management in an ambulatory setting. We evaluated adverse events and hospital re-admission using a database of 509 interscalene catheters inserted during ambulatory shoulder surgery. Adverse events were recorded for 34 (6.7%) patients (9 (...

journal_title：Anaesthesia

authors： Marhofer P,Anderl W,Heuberer P,Fritz M,Kimberger O,Marhofer D,Klug W,Blasl J

更新日期：2015-01-01 00:00:00

abstract：:Peripherally inserted central catheters are often positioned blindly in the central circulation, and this may result in high malposition rates, especially in critically ill patients. Recently, a new technology has been introduced (Sherlock 3CG Tip Positioning System) that uses an electro-magnetic system to guide posit...

journal_title：Anaesthesia

authors： Johnston AJ,Holder A,Bishop SM,See TC,Streater CT

更新日期：2014-12-01 00:00:00

abstract：:We systematically reviewed randomised controlled trials of the i-gel® vs different types of laryngeal mask airway in children. We included nine studies. There was no evidence for differences in: rate of insertion at first attempt; insertion time; ease of insertion; or gastric tube insertion. The mean (95% CI) orophary...

journal_title：Anaesthesia

authors： Choi GJ,Kang H,Baek CW,Jung YH,Woo YC,Cha YJ

更新日期：2014-11-01 00:00:00

abstract：:Concise guidelines are presented that recommend the method of choice for skin antisepsis before central neuraxial blockade. The Working Party specifically considered the concentration of antiseptic agent to use and its method of application. The advice presented is based on previously published guidelines, laboratory ...

journal_title：Anaesthesia

authors： Association of Anaesthetists of Great Britain and Ireland.,Obstetric Anaesthetists' Association,Regional Anaesthesia UK.,Association of Paediatric Anaesthetists of Great Britain and Ireland.,Campbell JP,Plaat F,Checketts MR,Bogod D,Tighe

更新日期：2014-11-01 00:00:00

abstract：:In this double-blind, randomised study, 100 patients undergoing open or conventional laparoscopic colorectal surgery received an intra-operative loading dose of dexmedetomidine 1 μg.kg(-1) followed by an infusion of 0.5 μg.kg(-1) .h(-1) , or a bolus and infusion of saline 0.9% of equivalent volume. Forty-six patients ...

journal_title：Anaesthesia

authors： Cheung CW,Qiu Q,Ying AC,Choi SW,Law WL,Irwin MG

更新日期：2014-11-01 00:00:00

abstract：:We systematically reviewed randomised controlled trials of peri-operative melatonin. We included 24 studies of 1794 participants that reported eight peri-operative outcomes: anxiety; analgesia; sleep quality; oxidative stress; emergence behaviour; anaesthetic requirements; steal induction; and safety. Compared with pl...

journal_title：Anaesthesia

authors： Andersen LP,Werner MU,Rosenberg J,Gögenur I

更新日期：2014-10-01 00:00:00

abstract：:Anatomical, neurological and behavioural research has suggested differences between the brains of right- and non-right-handed individuals, including differences in brain structure, electroencephalogram patterns, explicit memory and sleep architecture. Some studies have also found decreased longevity in left-handed ind...

journal_title：Anaesthesia

authors： Rao S,Huverserian AR,Ben Abdallah A,Lees K,Willingham MD,Burnside BA,Villafranca AJ,Glick DB,Jacobsohn E,Avidan MS

更新日期：2014-08-01 00:00:00

abstract：:The Confidential Enquiries into Maternal Deaths in the UK have recommended obstetric early warning systems for early identification of clinical deterioration to reduce maternal morbidity and mortality. This survey explored early warning systems currently used by maternity units in the UK. An electronic questionnaire w...

journal_title：Anaesthesia

authors： Isaacs RA,Wee MY,Bick DE,Beake S,Sheppard ZA,Thomas S,Hundley V,Smith GB,van Teijlingen E,Thomas PW,Members of the Modified Obstetric Early Warning Systems Research Group.

更新日期：2014-07-01 00:00:00

abstract：:In this prospective randomised study, we compared two techniques for i-gel(™) insertion. One hundred and eighty-one anaesthetised, paralysed adult patients were randomly allocated into one of two groups. In the standard group (n = 91), the i-gel was inserted using the standard technique. In the rotation group (n = 90)...

journal_title：Anaesthesia

authors： Kim HC,Yoo DH,Kim HJ,Jeon YT,Hwang JW,Park HP

更新日期：2014-07-01 00:00:00

abstract：:The objective of this study was to estimate the minimal effective anaesthetic concentrations of ropivacaine required to block the femoral nerve in 90% of patients. Forty-five patients who had knee surgery received ultrasound-guided femoral nerve block using 15 ml ropivacaine. The ropivacaine concentration given to a p...

journal_title：Anaesthesia

authors： Taha AM,Abd-Elmaksoud AM

更新日期：2014-07-01 00:00:00

abstract：:We compared the predictive performance of the existing Diprifusor and Schnider models, used for target-controlled infusion of propofol, with a new modification of the Diprifusor model (White) incorporating age and sex covariates. The bias and inaccuracy (precision) of each model were determined using computer simulati...

journal_title：Anaesthesia

authors： Glen JB,White M

更新日期：2014-06-01 00:00:00

abstract：:We studied the use of a new ke0 value (0.6 min(-1)) for the Marsh pharmacokinetic model for propofol. Speed of induction and side-effects produced were compared with three other target-controlled infusion systems. Eighty patients of ASA physical status 1-2 were studied in four groups in a prospective, randomised study...

journal_title：Anaesthesia

authors： Thomson AJ,Morrison G,Thomson E,Beattie C,Nimmo AF,Glen JB

更新日期：2014-05-01 00:00:00

abstract：:Posterior transversus abdominis plane blocks have been reported to be an effective method of providing analgesia after lower abdominal surgery. We compared the efficacy of a novel technique of providing continuous transversus abdominis plane analgesia with epidural analgesia in patients on an enhanced recovery program...

journal_title：Anaesthesia

authors： Niraj G,Kelkar A,Hart E,Horst C,Malik D,Yeow C,Singh B,Chaudhri S

更新日期：2014-04-01 00:00:00

abstract：:J waves appear on an electrocardiogram as an elevation of the J point in the terminal portion of the QRS complex. J waves are often benign, but may be associated with malignant ventricular arrhythmias. In some cases, such problems appear to have been precipitated by propofol infusions. We observed a sudden increase in...

journal_title：Anaesthesia

authors： Takaishi K,Kawahito S,Yamada H,Soeki T,Sata M,Kitahata H

更新日期：2014-02-01 00:00:00

abstract：:Malignant obstructive jaundice is associated with poor aerobic capacity. We measured oxygen consumption and oxygen extraction (arterial-venous oxygen content) in the legs of nine patients during cardiopulmonary exercise testing before pancreaticoduodenectomy. The median (IQR [range]) peak oxygen consumption was 67 (49...

journal_title：Anaesthesia

authors： Junejo MA,Siriwardena AK,Parker MJ

更新日期：2014-01-01 00:00:00

abstract：:The elderly have the ethical and legal equivalence of younger adults, yet are treated differently by society. Numerous recent reports have exposed poor inpatient care resulting in part from institutional ageism, which has moral and legal implications for healthcare providers. Morally, there is an argument for positive...

journal_title：Anaesthesia

authors： White SM

更新日期：2014-01-01 00:00:00

abstract：:We investigated the rate of injections interpreted as intravascular during imaging of lumbosacral transforaminal epidural injections, using fluoroscopy alone or with digital subtraction. We evaluated 732 injections performed on 348 patients: 8.1% (59/732) and 10.5% (77/732) of injections were interpreted as intravascu...

journal_title：Anaesthesia

authors： Kim YH,Park HJ,Moon DE

更新日期：2013-11-01 00:00:00

abstract：:This observational study assessed the frequency and risk factors of dental damage after classic direct laryngoscopy for tracheal intubation in 536 adult patients. The patients' sex, age, height, weight, dental condition, dental mobility, Mallampati class, interincisor gap, thyromental distance, neck circumference, and...

journal_title：Anaesthesia

authors： Mourão J,Neto J,Luís C,Moreno C,Barbosa J,Carvalho J,Tavares J

更新日期：2013-10-01 00:00:00

abstract：:Debate continues over the dose and methods of administration of oxytocin for the prevention of haemorrhage during caesarean section. We surveyed 206 lead obstetric anaesthetists in the UK to determine standard practice in their unit as well as any differences in practice for high-risk cases. There were 150 responses (...

journal_title：Anaesthesia

authors： West R,West S,Simons R,McGlennan A

更新日期：2013-10-01 00:00:00

abstract：:In this prospective study, cardiac output was measured in 38 intensive care unit patients before and after a fluid challenge, using both pulse contour analysis (Nexfin(®); BMEYE, Amsterdam, the Netherlands) and transthoracic echocardiography. The ability of the Nexfin device to detect significant changes in the veloci...

journal_title：Anaesthesia

authors： Taton O,Fagnoul D,De Backer D,Vincent JL

更新日期：2013-09-01 00:00:00

abstract：:We measured the distance 112 patients walked in 6 min, as well as their peak oxygen consumption pedalling a bicycle, week before scheduled resection of benign or malignant colorectal disease. The distance walked correlated with peak oxygen consumption, the former 'accounting' for about half the variation in the latter...

journal_title：Anaesthesia

authors： Lee L,Schwartzman K,Carli F,Zavorsky GS,Li C,Charlebois P,Stein B,Liberman AS,Fried GM,Feldman LS

更新日期：2013-08-01 00:00:00

abstract：:A 53-year-old man with hypopharyngeal stenosis following curative chemoradiotherapy for a tongue base tumour presented three years later for an attempt at pharyngeal dilatation. The first attempt 6 months previously was abandoned when awake fibreoptic intubation failed due to partial airway obstruction and desaturatio...

journal_title：Anaesthesia

authors： Paton L,Gupta S,Blacoe D

更新日期：2013-08-01 00:00:00

abstract：:In this prospective observational study we investigated the changes in cardiac index and mean arterial pressure in children when positioned prone for scoliosis correction surgery. Thirty children (ASA 1-2, aged 13-18 years) undergoing primary, idiopathic scoliosis repair were recruited. The cardiac index and mean arte...

journal_title：Anaesthesia

authors： Brown ZE,Görges M,Cooke E,Malherbe S,Dumont GA,Ansermino JM

更新日期：2013-07-01 00:00:00

abstract：:There is currently no consensus regarding how to intervene in anaesthetic-induced hypotension. Whether or not the balance between cerebral oxygen supply and demand is maintained lacks adequate elucidation. It is thus intriguing to explore how cerebral tissue oxygen saturation is affected by anaesthetic-induced hypoten...

journal_title：Anaesthesia

authors： Meng L,Gelb AW,McDonagh DL

更新日期：2013-07-01 00:00:00

abstract：:Although epidural analgesia is routinely used in many institutions for patients undergoing hepatic resection, there are unresolved issues regarding its safety and efficacy in this setting. We performed a review of papers published in the area of anaesthesia and analgesia for liver resection surgery and selected four a...

journal_title：Anaesthesia

authors： Tzimas P,Prout J,Papadopoulos G,Mallett SV

更新日期：2013-06-01 00:00:00

abstract：:To improve the analgesic efficiency and to simplify the administration of remifentanil for systemic analgesia in labour, we contrived a modified delivery regimen with a specific infusion profile and variable dosing and conducted a single-blind randomised crossover study to compare it with the previous 'classical' regi...

journal_title：Anaesthesia

authors： Jost A,Ban B,Kamenik M

更新日期：2013-03-01 00:00:00

abstract：:Increasing the calculated plasma concentration of propofol has been shown to increase choice reaction time and visual and auditory response times. We studied the relationship of reaction to a vibrating handset as the effect-site target-controlled propofol concentration was incrementally increased in 20 patients during...

journal_title：Anaesthesia

authors： Anderson KJ,Allam S,Chapman R,Kenny GN

更新日期：2013-02-01 00:00:00

abstract：:During the past decade, there has been a dramatic increase in the number of thoracic surgical procedures carried out in the UK. The current financial climate dictates that more efficient use of resources is necessary to meet escalating demands on healthcare. One potential means to achieve this is through the introduct...

journal_title：Anaesthesia

authors： Jones NL,Edmonds L,Ghosh S,Klein AA

更新日期：2013-02-01 00:00:00

abstract：:We compared the McGrath® Series 5 videolaryngoscope with the Macintosh laryngoscope in a simulated difficult airway, using manual in-line stabilisation in 88 anaesthestised patients of ASA physical status 1-2. The primary outcome was laryngoscopic view. Secondary outcomes included rates of successful tracheal intubati...

journal_title：Anaesthesia

authors： Taylor AM,Peck M,Launcelott S,Hung OR,Law JA,MacQuarrie K,McKeen D,George RB,Ngan J

更新日期：2013-02-01 00:00:00

abstract：:In this, the second of two articles covering specific medical emergencies, we discuss the definitions, epidemiology, pathophysiology, acute and chronic management of pulmonary embolus and acute severe asthma. ...

journal_title：Anaesthesia

authors： Somasundaram K,Ball J

更新日期：2013-01-01 00:00:00

abstract：:The ultrasonic cardiac output monitor is a non-invasive, continuous-wave Doppler monitor that can be used to measure cardiac output. Its accuracy and precision in peri-operative and critical care has been assessed with varied results. We conducted a meta-analysis to calculate a pooled mean bias, precision and percenta...

journal_title：Anaesthesia

authors： Chong SW,Peyton PJ

更新日期：2012-11-01 00:00:00